Medazine 1 G / 2 G Injection 1 g / 2 g Powder for Injection
PDF Leaflet Revision Date: 29 January 2021
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment and prophylaxis of infections due to susceptible organisms.
Dosage (summary)
Adults: 1-2 g every 8 hours; max 3 g every 6 hours for severe infections.
Special Populations
- Renal impairment
- Children under 2 years
Pregnancy & Breastfeeding
Safety in pregnancy and lactation not established; excreted in breast milk.
Key Drug Interactions
- Probenecid increases serum levels
- Enhanced nephrotoxicity with loop diuretics
- Antagonism with bacteriostatic agents
Contraindications
- Hypersensitivity to cefoxitin or u03b2-lactam antibiotics
- Porphyria
Common side effects
- Nausea
- Vomiting
- Diarrhoea
- Hypersensitivity reactions
- Thrombophlebitis
Counselling Points
- Report any signs of allergic reactions
- Monitor for gastrointestinal symptoms
- Avoid use in children under 2 years
Serious warnings
- Risk of pseudomembranous colitis
- Caution in gastrointestinal disease history
Important Disclaimer
The Medazine 1 G / 2 G Injection 1 g / 2 g Powder for Injection professional information leaflet below is the property of Aurogen South Africa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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