Meliora 60,0 mg Concentrate for solution for infusion
PDF Leaflet Revision Date: 24 January 2023
Clinical Summary
Quick overview from the medicine insert
Indication
Conditioning treatment prior to haematopoietic progenitor cell transplantation.
Dosage (summary)
0.8 mg/kg body weight as a 2-hour infusion every 6 hours for 4 days.
Special Populations
- Obese patients
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy; unknown if excreted in breast milk.
Key Drug Interactions
- Itraconazole
- Ketobemidone
- Paracetamol
- Phenytoin
Contraindications
- Hypersensitivity to busulfan
- Pregnancy
- Hepatic insufficiency
Common side effects
- Neutropenia
- Thrombocytopenia
- Anaemia
- Nausea
- Vomiting
Counselling Points
- Premedicate with anticonvulsants
- Monitor blood counts
- Avoid rapid IV injection
Serious warnings
- Profound myelosuppression
- Risk of seizures
- Hepatic veno-occlusive disease
Important Disclaimer
The Meliora 60,0 mg Concentrate for solution for infusion professional information leaflet below is the property of Emcure Pharmaceuticals Sa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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