Metpen 125/250 125 mg and 250mg Powder for oral solution
PDF Leaflet Revision Date: 30 January 2026
Clinical Summary
Quick overview from the medicine insert
Indication
Prophylaxis of rheumatic fever and treatment of mild to moderate infections.
Dosage (summary)
Adults: 125-250 mg every 6-8 hours; adjust for renal impairment.
Special Populations
- Renal impairment
Pregnancy & Breastfeeding
Use with caution in pregnancy; excreted in breast milk.
Key Drug Interactions
- Aminoglycosides
- Anticoagulants
- Bacteriostatic antibiotics
- Methotrexate
- Probenecid
Contraindications
- Hypersensitivity to penicillins
- Dysentery
- Typhus
- Penicillin resistant infections
Common side effects
- Gastrointestinal effects
- Hypersensitivity reactions
- Nausea
- Vomiting
Counselling Points
- Report any allergic reactions
- Take with caution if history of allergies
- Complete full course of therapy
Serious warnings
- Risk of anaphylaxis
- Caution in severe illness
- Prolonged use may cause superinfection
Important Disclaimer
The Metpen 125/250 125 mg and 250mg Powder for oral solution professional information leaflet below is the property of Austell Laboratories and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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