Motifine 75 mg Capsules, hard.
PDF Leaflet Revision Date: 21 July 2023
Clinical Summary
Quick overview from the medicine insert
Indication
Emergency treatment of acute gout attacks.
Dosage (summary)
Adults: 1 capsule daily, may increase to 2 capsules (max 150 mg/day). Max treatment: 3 days.
Onset of Action / Duration
Onset: 30 mins, Duration: 6-8 hours
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Not recommended in pregnancy or breastfeeding; may impair fertility.
Key Drug Interactions
- Increased risk of gastrointestinal bleeding with NSAIDs
- Enhanced effects of anticoagulants
- Increased methotrexate levels
Contraindications
- Hypersensitivity to diclofenac
- Severe renal and hepatic failure
- Pregnancy and lactation
- Heart failure
- History of gastrointestinal bleeding
Common side effects
- Gastrointestinal bleeding
- Nausea
- Headache
- Dizziness
Counselling Points
- Take with food
- Monitor for gastrointestinal symptoms
- Avoid use with other NSAIDs
Serious warnings
- Increased risk of cardiovascular events
- Gastrointestinal perforation
- Serious skin reactions
Important Disclaimer
The Motifine 75 mg Capsules, hard. professional information leaflet below is the property of Biotech Laboratories and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
Healthcare Professionals Only
This content is for registered healthcare professionals
Sign in or create a free account to read the full package insert.
Free for HPCSA-registered professionals. Powered by Medinsert.
