Oritaxim 500 and 1000mg sterile powder for injection
PDF Leaflet Revision Date: 08 August 2025
Clinical Summary
Quick overview from the medicine insert
Indication
Indicated for various infections including genito-urinary, skin, respiratory, gastrointestinal, and meningitis.
Dosage (summary)
Adults: 2 g daily in 2 injections; may increase to 3-4 g in severe cases. Pediatrics: 50-100 mg/kg daily.
Onset of Action / Duration
Onset: 30 mins, Duration: 6-8 hours
Special Populations
- Renal impairment
Pregnancy & Breastfeeding
Not established as safe in pregnancy; crosses into breast milk.
Key Drug Interactions
- Aminoglycosides
- Probenecid
Contraindications
- Hypersensitivity to cefotaxime
- History of immediate-type hypersensitivity to cephalosporins
Common side effects
- Superinfection
- Leukopenia
- Dizziness
- Diarrhea
Counselling Points
- Monitor for allergic reactions
- Report severe diarrhea
- Avoid driving if dizzy
Serious warnings
- Serious hypersensitivity reactions
- Pseudomembranous colitis
- Severe skin reactions
Important Disclaimer
The Oritaxim 500 and 1000mg sterile powder for injection professional information leaflet below is the property of Pharma-Q and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
Healthcare Professionals Only
This content is for registered healthcare professionals
Sign in or create a free account to read the full package insert.
Free for HPCSA-registered professionals. Powered by Medinsert.
