Pexola Er 0,375 mg; 0,75 mg; 1,5 mg; 3,0 mg XR tablets
PDF Leaflet Revision Date: 25 January 2023
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of idiopathic Parkinson's disease.
Dosage (summary)
Start at 0.375 mg daily, titrate weekly to max 4.5 mg.
Onset of Action / Duration
Onset: 6 hours, Duration: 8-12 hours
Special Populations
- Elderly
- Renal impairment
Pregnancy & Breastfeeding
Not recommended in pregnancy; inhibits lactation.
Key Drug Interactions
- Cimetidine
- Dopamine antagonists
- Alcohol and sedatives
Contraindications
- Hypersensitivity
- Renal impairment <50 mL/min
- Children <18 years
Common side effects
- Somnolence
- Nausea
- Dizziness
- Hallucinations
Counselling Points
- Avoid driving if drowsy
- Monitor for abnormal behaviors
- Taper off gradually
Serious warnings
- Risk of sudden sleep episodes
- Dopamine Dysregulation Syndrome
- Orthostatic hypotension
Important Disclaimer
The Pexola Er 0,375 mg; 0,75 mg; 1,5 mg; 3,0 mg XR tablets professional information leaflet below is the property of Ingelheim Pharmaceuticals and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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