Pleditex 24,0 mg SOLUTION FOR INJECTION
PDF Leaflet Revision Date: 22 March 2022
Clinical Summary
Quick overview from the medicine insert
Indication
Enhances mobilization of hematopoietic stem cells for autologous transplantation in lymphoma and multiple myeloma.
Dosage (summary)
0.24 mg/kg subcutaneously, administered 6-11 hours prior to apheresis after 4 days of G-CSF.
Onset of Action / Duration
Onset: 6-9 hours, Duration: Not specified
Special Populations
- Renal impairment
- Elderly
Pregnancy & Breastfeeding
Contraindicated in pregnancy; unknown if excreted in breast milk.
Key Drug Interactions
- G-CSF
- Rituximab
Contraindications
- Hypersensitivity to plerixafor
- Pregnancy
Common side effects
- Dizziness
- Nausea
- Fatigue
- Injection site reactions
Counselling Points
- Use effective contraception during treatment
- Avoid breastfeeding while on treatment
- Caution advised when driving or operating machinery
Serious warnings
- Potential for leukemic cell mobilization
- Monitor white blood cell and platelet counts
Important Disclaimer
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