Mozobil 20mg / 1ml Injection

    Mozobil 20mg / 1ml Injection

    S4
    PDF Leaflet Revision Date: 12 May 2023

    API: Plerixafor | Company: Sanofi-Aventis

    Clinical Summary

    Quick overview from the medicine insert

    Indication

    Enhances mobilisation of hematopoietic stem cells for autologous transplantation in lymphoma and multiple myeloma.

    Dosage (summary)

    0.24 mg/kg SC, administered 6-11 hours prior to apheresis after 4 days of G-CSF.

    Onset of Action / Duration

    Onset: 30-60 mins, Duration: 4-18 hours

    Special Populations

    • Renal impairment
    • Elderly

    Pregnancy & Breastfeeding

    May cause fetal harm; not established in lactation.

    Key Drug Interactions

    • G-CSF
    • Rituximab

    Contraindications

    • Hypersensitivity
    • Pregnancy
    • Lactation

    Common side effects

    • Diarrhoea
    • Nausea
    • Injection site reactions
    • Fatigue

    Counselling Points

    • Use effective contraception during treatment
    • Do not breastfeed while on treatment
    • Report any abdominal pain or discomfort

    Serious warnings

    • Tumor cell mobilization in leukemia
    • Monitor leukocyte and platelet counts
    Important Disclaimer

    The Mozobil 20mg / 1ml Injection professional information leaflet below is the property of Sanofi-Aventis and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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