Provera 100 Mg And 500 Mg Tablets 100 mg and 500 mg Tablets.
PDF Leaflet Revision Date: 12 December 2025
Clinical Summary
Quick overview from the medicine insert
Indication
Palliative treatment of recurrent/metastatic cancers.
Dosage (summary)
Endometrial/renal cancer: 200-600 mg/day; Breast cancer: 400-1200 mg/day.
Special Populations
- Elderly
- Diabetics
- History of depression
Pregnancy & Breastfeeding
Contraindicated in pregnancy; not recommended during breastfeeding.
Key Drug Interactions
- Aminoglutethimide
- CYP3A4 inducers/inhibitors
Contraindications
- Hypersensitivity
- Pregnancy
- Undiagnosed vaginal bleeding
- Severe liver dysfunction
Common side effects
- Weight gain
- Fluid retention
- Depression
- Dizziness
- Nausea
Counselling Points
- Monitor for mood changes
- Avoid pregnancy
- Inform about potential side effects
- Do not breastfeed while on therapy
Serious warnings
- Increased risk of breast cancer
- Cardiovascular events
- Thromboembolism risk
- Meningioma risk
Important Disclaimer
The Provera 100 Mg And 500 Mg Tablets 100 mg and 500 mg Tablets. professional information leaflet below is the property of Pfizer Laboratories and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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