Puresis 40 mg Tablet
PDF Leaflet Revision Date: 19 May 1976
Clinical Summary
Quick overview from the medicine insert
Indication
Diuretic for ascites, cardiac edema, hypertension, and pregnancy-related edema.
Dosage (summary)
Initial: 1-3 tablets; Maintenance: 0.5-1 tablet daily.
Onset of Action / Duration
Onset: 30 mins, Duration: 4-5 hours
Special Populations
- Hepatic impairment
- Renal impairment
- Elderly
Pregnancy & Breastfeeding
Use with caution in pregnancy; contraindicated in lactation.
Key Drug Interactions
- Nephrotoxicity with cephaloridine
- Enhanced toxicity of digitalis
- Reduced effects with phenytoin
Contraindications
- Hypersensitivity to furosemide
- Hepatic coma
- Electrolyte depletion
- Severe renal disease
Common side effects
- Dermatitis
- Dizziness
- Nausea
- Hypokalaemia
- Tinnitus
Counselling Points
- Monitor potassium levels
- Report signs of dehydration
- Avoid rapid correction of edema
Serious warnings
- Caution in pregnancy
- Risk of dehydration
- May cause digitalis toxicity
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