Rimactazid 150/75 150mg. 75mg Tablet

    Rimactazid 150/75 150mg. 75mg Tablet

    S4
    PDF Leaflet Revision Date: 02 May 2019

    API: Rifampicin Isoniazid | Company: Sandoz

    Clinical Summary

    Quick overview from the medicine insert

    Indication

    Pulmonary tuberculosis in the continuous phase of treatment.

    Dosage (summary)

    Rifampicin 10 mg/kg (max 600 mg), Isoniazid 5 mg/kg (max 300 mg) daily.

    Special Populations

    • Renal impairment
    • Hepatic impairment
    • Diabetes mellitus
    • Chronic alcoholism

    Pregnancy & Breastfeeding

    Safety during pregnancy and lactation not established; caution advised.

    Key Drug Interactions

    • Halothane
    • Ketoconazole
    • Phenytoin
    • Warfarin
    • Oral contraceptives

    Contraindications

    • Hypersensitivity to rifamycins or isoniazid
    • Jaundice
    • Liver damage

    Common side effects

    • Liver dysfunction
    • Nausea
    • Vomiting
    • Skin rashes
    • Thrombocytopenia

    Counselling Points

    • Monitor for signs of liver damage
    • Avoid alcohol
    • Use non-hormonal contraceptives

    Serious warnings

    • Monitor liver function
    • Risk of severe hepatitis
    • May exacerbate convulsive disorders
    Important Disclaimer

    The Rimactazid 150/75 150mg. 75mg Tablet professional information leaflet below is the property of Sandoz and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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