Rivotril Range 0.5 mg/ 2 mg/ 1 mg/m_/ 2.5 mg/m_ Tablets. Injection. Drops

Rivotril Range 0.5 mg/ 2 mg/ 1 mg/m_/ 2.5 mg/m_ Tablets. Injection. Drops

S5
PDF Leaflet Revision Date: 02 March 2022

API: Clonazepam | Company: Roche Products

Clinical Summary

Quick overview from the medicine insert

Indication

Epilepsy and Panic Disorder.

Dosage (summary)

Adults: Initial 1.5 mg/day, max 20 mg/day. Adjust based on response.

Onset of Action / Duration

Onset: 30-60 mins, Duration: 8-12 hours.

Special Populations

  • Elderly
  • Renal impairment
  • Hepatic impairment

Pregnancy & Breastfeeding

Use only if necessary in pregnancy; contraindicated in breastfeeding.

Key Drug Interactions

  • CNS depressants
  • Phenytoin
  • Valproate

Contraindications

  • Hypersensitivity to clonazepam
  • Severe respiratory insufficiency
  • Severe hepatic impairment
  • Acute narrow angle glaucoma
  • Sleep apnoea

Common side effects

  • Somnolence
  • Headache
  • Dizziness
  • Fatigue
  • Nausea

Counselling Points

  • Avoid alcohol
  • Monitor for sedation
  • Gradual dose tapering recommended

Serious warnings

  • Risk of dependence
  • Withdrawal symptoms
  • Paradoxical reactions
Important Disclaimer

The Rivotril Range 0.5 mg/ 2 mg/ 1 mg/m_/ 2.5 mg/m_ Tablets. Injection. Drops professional information leaflet below is the property of Roche Products and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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