Tecentriq 840 Mg. Tecentriq 1 200 Mg. 840 mg. 1 200 mg Concentrate for solution for infusion

Tecentriq 840 Mg. Tecentriq 1 200 Mg. 840 mg. 1 200 mg Concentrate for solution for infusion

S4
PDF Leaflet Revision Date: 13 February 2025

API: Atezolizumab | Company: Roche Products

Clinical Summary

Quick overview from the medicine insert

Indication

Treatment of various cancers including metastatic urothelial carcinoma and non-small cell lung cancer.

Dosage (summary)

840 mg every 2 weeks or 1,200 mg every 3 weeks; adjust based on indication.

Special Populations

  • Renal impairment
  • Hepatic impairment
  • Geriatric patients

Pregnancy & Breastfeeding

Contraindicated in pregnancy; avoid breastfeeding during treatment and for 5 months after.

Key Drug Interactions

  • Avoid systemic corticosteroids before starting
  • No significant drug-drug interactions expected

Contraindications

  • Hypersensitivity to atezolizumab
  • Use of live vaccines

Common side effects

  • Fatigue
  • Nausea
  • Diarrhea
  • Rash
  • Infusion-related reactions

Counselling Points

  • Monitor for signs of immune-mediated reactions
  • Advise on contraception during treatment
  • Inform about potential infusion reactions

Serious warnings

  • Immune-mediated pneumonitis
  • Hepatitis
  • Colitis
  • Endocrinopathies
  • Severe cutaneous adverse reactions
Important Disclaimer

The Tecentriq 840 Mg. Tecentriq 1 200 Mg. 840 mg. 1 200 mg Concentrate for solution for infusion professional information leaflet below is the property of Roche Products and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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