Tecentriq 840 Mg. Tecentriq 1 200 Mg. 840 mg. 1 200 mg Concentrate for solution for infusion
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of various cancers including metastatic urothelial carcinoma and non-small cell lung cancer.
Dosage (summary)
840 mg every 2 weeks or 1,200 mg every 3 weeks; adjust based on indication.
Special Populations
- Renal impairment
- Hepatic impairment
- Geriatric patients
Pregnancy & Breastfeeding
Contraindicated in pregnancy; avoid breastfeeding during treatment and for 5 months after.
Key Drug Interactions
- Avoid systemic corticosteroids before starting
- No significant drug-drug interactions expected
Contraindications
- Hypersensitivity to atezolizumab
- Use of live vaccines
Common side effects
- Fatigue
- Nausea
- Diarrhea
- Rash
- Infusion-related reactions
Counselling Points
- Monitor for signs of immune-mediated reactions
- Advise on contraception during treatment
- Inform about potential infusion reactions
Serious warnings
- Immune-mediated pneumonitis
- Hepatitis
- Colitis
- Endocrinopathies
- Severe cutaneous adverse reactions
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