Rocephin Range 250 mg. 500 mg. 1 g. 2 g Injection
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of various bacterial infections.
Dosage (summary)
Adults: 1-2 g once daily; up to 4 g for severe cases.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Crosses placenta; safety in pregnancy not established. Excreted in breast milk.
Key Drug Interactions
- Calcium-containing products
- Aminoglycosides
- Vitamin K antagonists
Contraindications
- Hypersensitivity to ceftriaxone
- Premature neonates
- Hyperbilirubinemic newborns
Common side effects
- Eosinophilia
- Leucopenia
- Diarrhoea
- Rash
- Increased hepatic enzymes
Counselling Points
- Monitor for allergic reactions
- Avoid calcium-containing solutions
- Report severe diarrhoea
Serious warnings
- Serious hypersensitivity reactions
- Clostridium difficile associated diarrhoea
- Calcium-ceftriaxone precipitates
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