Rocephin Range 250 mg. 500 mg. 1 g. 2 g Injection

Rocephin Range 250 mg. 500 mg. 1 g. 2 g Injection

S4
PDF Leaflet Revision Date: 31 October 2022

API: Ceftriaxone | Company: Roche Products

Clinical Summary

Quick overview from the medicine insert

Indication

Treatment of various bacterial infections.

Dosage (summary)

Adults: 1-2 g once daily; up to 4 g for severe cases.

Special Populations

  • Elderly
  • Renal impairment
  • Hepatic impairment

Pregnancy & Breastfeeding

Crosses placenta; safety in pregnancy not established. Excreted in breast milk.

Key Drug Interactions

  • Calcium-containing products
  • Aminoglycosides
  • Vitamin K antagonists

Contraindications

  • Hypersensitivity to ceftriaxone
  • Premature neonates
  • Hyperbilirubinemic newborns

Common side effects

  • Eosinophilia
  • Leucopenia
  • Diarrhoea
  • Rash
  • Increased hepatic enzymes

Counselling Points

  • Monitor for allergic reactions
  • Avoid calcium-containing solutions
  • Report severe diarrhoea

Serious warnings

  • Serious hypersensitivity reactions
  • Clostridium difficile associated diarrhoea
  • Calcium-ceftriaxone precipitates
Important Disclaimer

The Rocephin Range 250 mg. 500 mg. 1 g. 2 g Injection professional information leaflet below is the property of Roche Products and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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