Sandimmun. Sandimmun Neoral 50 mg per 1 ml. 100 mg per 1 ml. 25 mg. 100 mg Ampoule. Drink Solution. Capsule
PDF Leaflet Revision Date: 13 January 2025
Clinical Summary
Quick overview from the medicine insert
Indication
Prophylaxis of graft rejection and treatment of severe psoriasis, rheumatoid arthritis, and atopic dermatitis.
Dosage (summary)
Transplant: 10-15 mg/kg pre-op, then 2-6 mg/kg; Psoriasis: 2.5-5 mg/kg; RA: 2.5-5 mg/kg.
Special Populations
- Renal impairment
- Hepatic impairment
- Elderly
Pregnancy & Breastfeeding
Use only if benefits outweigh risks; avoid breastfeeding.
Key Drug Interactions
- Grapefruit juice increases ciclosporin levels
- Avoid live vaccines
- Caution with potassium-sparing diuretics
Contraindications
- Hypersensitivity to ciclosporin
- Abnormal renal function
- Uncontrolled hypertension
Common side effects
- Renal dysfunction
- Hypertension
- Tremor
- Nausea
- Diarrhoea
Counselling Points
- Monitor renal function regularly
- Avoid grapefruit juice
- Report any signs of infection or unusual symptoms
Serious warnings
- Increased risk of malignancies
- Risk of infections
- Anaphylactoid reactions with IV use
Important Disclaimer
The Sandimmun. Sandimmun Neoral 50 mg per 1 ml. 100 mg per 1 ml. 25 mg. 100 mg Ampoule. Drink Solution. Capsule professional information leaflet below is the property of Novartis South Africa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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