Sertra Tablets 50 Mg 50 mg Tablet

    Sertra Tablets 50 Mg 50 mg Tablet

    S5
    PDF Leaflet Revision Date: 29 September 2023


    Clinical Summary

    Quick overview from the medicine insert

    Indication

    Major depressive disorder, OCD, panic disorder.

    Dosage (summary)

    Starting dose 50 mg daily; may titrate to 150-200 mg for difficult cases.

    Onset of Action / Duration

    Onset: 7 days, Duration: 24 hours

    Special Populations

    • Elderly
    • Hepatic impairment
    • Renal impairment

    Pregnancy & Breastfeeding

    Not established; avoid breastfeeding.

    Key Drug Interactions

    • MAOIs
    • Pimozide
    • Lithium
    • CNS depressants

    Contraindications

    • Hypersensitivity to sertraline
    • MAOI use
    • Children < 18 with OCD and depression

    Common side effects

    • Insomnia
    • Dizziness
    • Nausea
    • Dry mouth
    • Sexual dysfunction

    Counselling Points

    • Monitor for worsening depression
    • Avoid alcohol
    • Taper off to discontinue

    Serious warnings

    • Serotonin syndrome
    • QTc prolongation
    • Suicidal thoughts
    Important Disclaimer

    The Sertra Tablets 50 Mg 50 mg Tablet professional information leaflet below is the property of Upjohn South Africa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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