Sevoflurane Baxter 100 mg Liquid for inhalation
Clinical Summary
Quick overview from the medicine insert
Indication
Induction and maintenance of general anaesthesia.
Dosage (summary)
Individualised; typically 0.5-3% for maintenance.
Onset of Action / Duration
Onset: <2 mins, Duration: variable.
Special Populations
- Elderly
- Paediatric patients
- Renal impairment
- Liver disease
- Mitochondrial disorders
Pregnancy & Breastfeeding
Caution in pregnancy; safety not established. Unknown if excreted in breast milk.
Key Drug Interactions
- Nitrous oxide decreases MAC
- Benzodiazepines and opioids may enhance effects
- Neuromuscular blockers require dosage adjustment
Contraindications
- Hypersensitivity to sevoflurane
- History of malignant hyperthermia
- Neuromuscular disease
- General anaesthesia contraindicated
Common side effects
- Nausea
- Vomiting
- Dizziness
- Hypotension
- Bradycardia
Counselling Points
- Avoid driving for 24 hours post-anaesthesia
- Monitor for signs of respiratory depression
- Inform about potential for postoperative nausea
Serious warnings
- Respiratory depression risk
- Potential for malignant hyperthermia
- Caution in patients with coronary disease
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