Uromitexan 400 Mg Injection 400 mg Injection
Clinical Summary
Quick overview from the medicine insert
Indication
Reduces urinary toxicity from oxazaphosphorines.
Dosage (summary)
IV injection of 20% of oxazaphosphorine dose at 0, 4, and 8 hours.
Special Populations
- Elderly patients
- Paediatric patients (<16 years)
Pregnancy & Breastfeeding
Not established; avoid in pregnancy and lactation.
Key Drug Interactions
- Incompatible with cisplatin, carboplatin, nitrogen mustard
- Inactivates epirubicin
Contraindications
- Hypersensitivity to UROMITEXAN or thiol compounds
Common side effects
- Headache
- Infusion site reactions
- Abdominal pain
- Light-headedness
- Nausea
Counselling Points
- Monitor for hypersensitivity reactions
- Maintain adequate hydration
- Inspect for particulate matter before use
Serious warnings
- Potential for severe hypersensitivity reactions
- Does not prevent all adverse effects of oxazaphosphorines
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