Simvacor 10mg, 20mg, 40 mg FC tablets.
PDF Leaflet Revision Date: 14 January 2026
Clinical Summary
Quick overview from the medicine insert
Indication
Indicated for hypercholesterolaemia and coronary heart disease.
Dosage (summary)
Adults: Initial 10 mg daily for hypercholesterolaemia; 20 mg daily for coronary heart disease, max 80 mg.
Special Populations
- Renal impairment
- Elderly
Pregnancy & Breastfeeding
Contraindicated in pregnancy and lactation; fetotoxic and teratogenic effects noted.
Key Drug Interactions
- CYP3A4 inhibitors
- Gemfibrozil
- Cyclosporin
Contraindications
- Hypersensitivity
- Liver disease
- Pregnancy
- Lactation
Common side effects
- Myalgia
- Nausea
- Headache
- Dizziness
Counselling Points
- Report unexplained muscle pain
- Avoid grapefruit juice
- Monitor liver function tests
Serious warnings
- Risk of myopathy/rhabdomyolysis
- Hepatic failure
- Cognitive impairment
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