Suprefact 3-Month Depot 3.3mg. 9.9mg Implant

    Suprefact 3-Month Depot 3.3mg. 9.9mg Implant

    S4
    PDF Leaflet Revision Date: 06 June 2018


    Clinical Summary

    Quick overview from the medicine insert

    Indication

    Advanced prostatic cancer requiring testosterone suppression.

    Dosage (summary)

    One implant (9.45 mg buserelin) subcutaneously every 3 months.

    Onset of Action / Duration

    Onset: 2-4 weeks, Duration: 3 months

    Special Populations

    • Patients with hypertension
    • Diabetic patients
    • History of depression

    Pregnancy & Breastfeeding

    Not recommended; safety not established.

    Key Drug Interactions

    • Antidiabetic medicines
    • QT prolonging drugs

    Contraindications

    • Hypersensitivity to buserelin acetate
    • Post-surgical testosterone suppression

    Common side effects

    • Loss of libido
    • Hot flushes
    • Dizziness
    • Injection site pain

    Counselling Points

    • Monitor blood pressure and glucose levels
    • Report any signs of depression
    • Avoid driving if experiencing dizziness

    Serious warnings

    • Risk of osteoporosis
    • Monitor for QT prolongation
    • Adjunctive anti-androgen therapy recommended
    Important Disclaimer

    The Suprefact 3-Month Depot 3.3mg. 9.9mg Implant professional information leaflet below is the property of Pharmaco Distribution and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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