Syntometrine 1 ml Injection
PDF Leaflet Revision Date: 15 December 2022
Clinical Summary
Quick overview from the medicine insert
Indication
Active management of third stage of labour and prevention/treatment of postpartum haemorrhage.
Dosage (summary)
1 ml intramuscularly after delivery of the shoulder or immediately after delivery of the child.
Onset of Action / Duration
Onset: 7 mins, Duration: Not specified
Special Populations
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated during pregnancy and first two stages of labour; excreted in breast milk, may suppress lactation.
Key Drug Interactions
- CYP3A4 inhibitors
- Vasoconstrictors
- Prostaglandins
Contraindications
- Hypersensitivity
- Pregnancy
- Uterine inertia
- Severe toxaemia
- Hypertension
- Cardiac disease
Common side effects
- Hypertension
- Dizziness
- Nausea
- Vomiting
- Headache
Counselling Points
- Avoid driving or operating machinery
- Monitor for dizziness and hypotension
- Report any adverse reactions
Serious warnings
- Anaphylaxis in latex allergy
- Potentially arrhythmogenic
- Caution in coronary artery disease
Important Disclaimer
The Syntometrine 1 ml Injection professional information leaflet below is the property of Adcock Ingram Critical Care and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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