Topiramate 25 / 50 / 100 Unicorn 25 mg / 50 mg /100 mg FC tablets
PDF Leaflet Revision Date: 8 September 2022
Clinical Summary
Quick overview from the medicine insert
Indication
Monotherapy and adjunctive therapy for epilepsy.
Dosage (summary)
Adults: Start at 25 mg nightly, target 100 mg/day, max 500 mg. Children: Start at 0.5-1 mg/kg nightly, target 100-400 mg/day.
Special Populations
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and breastfeeding; teratogenic effects observed.
Key Drug Interactions
- Phenytoin
- Carbamazepine
- Valproic acid
- Oral contraceptives
Contraindications
- Hypersensitivity to topiramate
- Children under 2 years
- Pregnancy
- Lactation
Common side effects
- Drowsiness
- Dizziness
- Nausea
- Weight loss
- Metabolic acidosis
Counselling Points
- Monitor for mood changes
- Stay hydrated
- Avoid abrupt withdrawal
- Use effective contraception in women of childbearing potential
Serious warnings
- Suicidal ideation
- Serious skin reactions
- Acute myopia and glaucoma
- Hyperammonaemia
Important Disclaimer
The Topiramate 25 / 50 / 100 Unicorn 25 mg / 50 mg /100 mg FC tablets professional information leaflet below is the property of Zydus Healthcare Sa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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