Tremofid 20 mg Tablet
PDF Leaflet Revision Date: 09 May 2023
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of breast cancer.
Dosage (summary)
20 mg to 40 mg daily, in divided doses or as a single dose.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and breastfeeding.
Key Drug Interactions
- Warfarin
- CYP2D6 inhibitors
- Cytotoxic medicines
Contraindications
- Hypersensitivity to tamoxifen
- Pregnancy
- Breastfeeding
- Concomitant coumarin-type anticoagulants
Common side effects
- Hot flushes
- Menstrual irregularities
- Nausea
- Fatigue
Counselling Points
- Avoid pregnancy during treatment
- Monitor for abnormal gynaecological symptoms
- Use caution when driving due to visual disturbances
Serious warnings
- Increased risk of endometrial cancer
- Thromboembolic events
- Liver enzyme changes
Important Disclaimer
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