Verqalif 2,5 mg, 5 mg & 10 mg Tablet

    Verqalif 2,5 mg, 5 mg & 10 mg Tablet

    S4
    PDF Leaflet Revision Date: 15 August 2023

    API: Vericiguat | Company: Bayer

    Clinical Summary

    Quick overview from the medicine insert

    Indication

    Treatment of symptomatic chronic heart failure with reduced ejection fraction.

    Dosage (summary)

    Start at 2.5 mg once daily, titrate to 10 mg once daily as tolerated.

    Special Populations

    • Elderly
    • Renal impairment
    • Hepatic impairment

    Pregnancy & Breastfeeding

    Not recommended during pregnancy; unknown if excreted in breast milk.

    Key Drug Interactions

    • Concomitant use with other sGC stimulators
    • PDE5 inhibitors

    Contraindications

    • Hypersensitivity to vericiguat or excipients
    • Severe renal impairment (eGFR <15 mL/min/1.73 mu00b2)
    • Severe hepatic impairment (Child-Pugh class C)

    Common side effects

    • Hypotension
    • Dizziness
    • Nausea
    • Headache

    Counselling Points

    • Take with food
    • Monitor blood pressure regularly
    • Report any symptoms of hypotension

    Serious warnings

    • Risk of symptomatic hypotension
    • Not studied in patients with SBP <100 mmHg
    Important Disclaimer

    The Verqalif 2,5 mg, 5 mg & 10 mg Tablet professional information leaflet below is the property of Bayer and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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