VoXRa Xl 150mg. 300mg Tablet
PDF Leaflet Revision Date: 23 April 2024
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of depression as per DSM IV criteria.
Dosage (summary)
Initial: 150 mg once daily; may increase to 300 mg once daily if needed.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Not established; avoid unless necessary. Contraindicated in breastfeeding.
Key Drug Interactions
- CYP2B6 inhibitors
- MAOIs
- Alcohol
Contraindications
- Hypersensitivity to bupropion
- Seizure disorder
- Patients under 18 years
- Bulimia or anorexia nervosa
- Moderate to severe hepatic cirrhosis
Common side effects
- Insomnia
- Headache
- Dry mouth
- Increased blood pressure
Counselling Points
- Monitor for worsening depression or suicidal thoughts.
- Avoid alcohol during treatment.
- Do not crush or chew tablets.
Serious warnings
- Risk of seizures
- Suicidal ideation in young adults
- Neuropsychiatric symptoms
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