Winthrop Isoniazid 100 mg & 300 mg Tablets
PDF Leaflet Revision Date: 23 June 2022
Clinical Summary
Quick overview from the medicine insert
Indication
Prophylaxis and treatment of tuberculosis.
Dosage (summary)
Adults: 3-5 mg/kg (max 300 mg); Children: 10-20 mg/kg.
Special Populations
- Hepatic impairment
- Renal impairment
- Elderly
Pregnancy & Breastfeeding
Not established; avoid in pregnancy and lactation.
Key Drug Interactions
- Antiepileptics
- Oral anticoagulants
- Alcohol
- Aluminium-containing antacids
Contraindications
- Hypersensitivity to isoniazid
- Drug-induced liver disease
Common side effects
- Hepatotoxicity
- Dizziness
- Nausea
- Rash
Counselling Points
- Take on an empty stomach
- Monitor for liver symptoms
- Avoid alcohol
Serious warnings
- Severe hepatitis risk
- SJS and TEN
- DRESS syndrome
Important Disclaimer
The Winthrop Isoniazid 100 mg & 300 mg Tablets professional information leaflet below is the property of Sanofi-Aventis South Africa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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