Xigduo XR FC tablets
PDF Leaflet Revision Date: 12 February 2025
Clinical Summary
Quick overview from the medicine insert
Indication
For type 2 diabetes mellitus as an adjunct to diet and exercise.
Dosage (summary)
Dapagliflozin 10 mg once daily; Metformin starting at 500 mg, titrate to 2000 mg.
Special Populations
- Renal impairment
- Hepatic impairment
- Elderly patients
Pregnancy & Breastfeeding
Contraindicated in pregnancy and breastfeeding.
Key Drug Interactions
- Insulin and insulin secretagogues may increase hypoglycemia risk.
- Cationic medicines may interact with metformin.
Contraindications
- Type 1 diabetes
- Severe renal impairment
- Acute or chronic metabolic acidosis
- Pregnancy and breastfeeding
Common side effects
- Genital infections
- Urinary tract infections
- Diabetic ketoacidosis
Counselling Points
- Take with evening meal.
- Do not crush or chew tablets.
- Monitor for signs of acidosis.
Serious warnings
- Risk of lactic acidosis
- Risk of ketoacidosis
Important Disclaimer
The Xigduo XR FC tablets professional information leaflet below is the property of Astrazeneca Pharmaceuticals and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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