Fungizone Intravenous Injection 50 mg Injection
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of progressive, potentially life-threatening fungal infections.
Dosage (summary)
Initial dose: 0.25 mg/kg/day, may increase to 0.5-1.5 mg/kg based on tolerance.
Special Populations
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Safety in pregnancy not established; avoid breastfeeding.
Key Drug Interactions
- Nephrotoxic medications
- Corticosteroids
- Flucytosine
- Imidazoles
Contraindications
- Hypersensitivity to amphotericin B or components
Common side effects
- Nausea
- Vomiting
- Chills
- Hypokalaemia
- Hypotension
Counselling Points
- Administer under close supervision
- Monitor for intolerance
- Avoid rapid infusion
Serious warnings
- Potentially fatal cardiac arrest with overdose
- Monitor renal function
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