Imuran 50 Mg Film-Coated Tablets 50 mg Film-coated tablets
PDF Leaflet Revision Date: 23 June 2021
Clinical Summary
Quick overview from the medicine insert
Indication
Immunosuppressant for organ transplantation and autoimmune diseases.
Dosage (summary)
Loading: up to 5 mg/kg/day; Maintenance: 1-4 mg/kg/day orally or IV if oral not tolerated.
Onset of Action / Duration
Onset: weeks to months, Duration: long-term therapy required.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and breastfeeding; potential fetal harm.
Key Drug Interactions
- Allopurinol (reduce IMURAN dose to 25%)
- Ribavirin (not advised)
- TPMT inhibitors
Contraindications
- Hypersensitivity to azathioprine
- Pregnancy
- Previous alkylating agent treatment
Common side effects
- Infections
- Leukopenia
- Nausea
- Alopecia
- Liver dysfunction
Counselling Points
- Avoid live vaccines during treatment
- Report signs of infection or bleeding
- Monitor for liver function changes
Serious warnings
- Risk of malignancies
- Bone marrow suppression
- Hepatotoxicity
Important Disclaimer
The Imuran 50 Mg Film-Coated Tablets 50 mg Film-coated tablets professional information leaflet below is the property of Pharmacare Limited and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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