Equiben 25 & 100 25 mg, 100 mg Powder for concentrate for solution for infusion

Equiben 25 & 100 25 mg, 100 mg Powder for concentrate for solution for infusion

S4
PDF Leaflet Revision Date: 24 July 2025


Clinical Summary

Quick overview from the medicine insert

Indication

First-line treatment for specific hematological malignancies.

Dosage (summary)

100 mg/mu00b2 on days 1 and 2 for CLL; 90 mg/mu00b2 with rituximab for NHL; 120-150 mg/mu00b2 for multiple myeloma.

Onset of Action / Duration

Onset: 30 mins, Duration: 4 weeks

Special Populations

  • Hepatic impairment
  • Renal impairment
  • Elderly patients

Pregnancy & Breastfeeding

Contraindicated in pregnancy and breastfeeding.

Key Drug Interactions

  • Myelosuppressive agents
  • Ciclosporin
  • Tacrolimus

Contraindications

  • Hypersensitivity
  • Severe hepatic impairment
  • Severe bone marrow suppression
  • Pregnancy
  • Lactation

Common side effects

  • Leukopenia
  • Thrombocytopenia
  • Nausea
  • Vomiting
  • Skin reactions

Counselling Points

  • Monitor for signs of infection
  • Avoid pregnancy
  • Use contraception
  • Report severe skin reactions

Serious warnings

  • Myelosuppression
  • Infections
  • Hepatitis B reactivation
  • Skin reactions
  • Cardiac disorders
Important Disclaimer

The Equiben 25 & 100 25 mg, 100 mg Powder for concentrate for solution for infusion professional information leaflet below is the property of Equity Pharmaceuticals and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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