Klarithran Mr 500 500 mg Tablet.
PDF Leaflet Revision Date: 23 August 2023
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of mild to moderately severe infections.
Dosage (summary)
500 mg once daily with food; may increase to 2 x 500 mg for severe infections.
Special Populations
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Safety in pregnancy/lactation not established; excreted in breast milk.
Key Drug Interactions
- Astemizole
- Warfarin
- Digoxin
- Simvastatin
- Rifabutin
- Theophylline
Contraindications
- Hypersensitivity to macrolides
- Concomitant use with certain drugs
- Porphyria
Common side effects
- Nausea
- Vomiting
- Diarrhoea
- Headache
- QT prolongation
Counselling Points
- Take with food
- Monitor for signs of hepatic dysfunction
- Report any unusual symptoms
Serious warnings
- Hepatic dysfunction
- Rhabdomyolysis risk
- Severe renal impairment
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