Clarihexal 125 P/ Clarihexal 250 P 125 mg/ 250 mg Granules for oral suspension

    Clarihexal 125 P/ Clarihexal 250 P 125 mg/ 250 mg Granules for oral suspension

    S4
    PDF Leaflet Revision Date: 05 August 2021

    API: Clarithromycin | Company: Sandoz Sa

    Clinical Summary

    Quick overview from the medicine insert

    Indication

    Treatment of mild to moderate severe infections.

    Dosage (summary)

    Adults: 250 mg twice daily; severe infections: 500 mg twice daily.

    Special Populations

    • Renal impairment
    • Hepatic impairment

    Pregnancy & Breastfeeding

    Safety in pregnancy and breastfeeding not established; potential risks exist.

    Key Drug Interactions

    • Statins (lovastatin, simvastatin)
    • Ergot alkaloids
    • Oral midazolam

    Contraindications

    • Hypersensitivity to macrolides
    • QT prolongation history
    • Severe hepatic failure

    Common side effects

    • Nausea
    • Diarrhoea
    • Headache
    • Rash

    Counselling Points

    • Take with or without food
    • Monitor for signs of liver dysfunction
    • Avoid alcohol

    Serious warnings

    • Risk of QT prolongation
    • Hepatic dysfunction
    • Pseudomembranous colitis
    Important Disclaimer

    The Clarihexal 125 P/ Clarihexal 250 P 125 mg/ 250 mg Granules for oral suspension professional information leaflet below is the property of Sandoz Sa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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