Cosmegen 0,5 Mg 0,5 mg POWDER FOR SOLUTION FOR INJECTION
PDF Leaflet Revision Date: 6 September 2022
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of various cancers including nephroblastoma and rhabdomyosarcoma.
Dosage (summary)
Adults: 15-45 mcg/kg IV for 5 days; adjust for toxicity.
Special Populations
- Elderly
- Infants
Pregnancy & Breastfeeding
Contraindicated in pregnancy and breastfeeding due to teratogenic effects.
Key Drug Interactions
- Potentiates effects of X-ray therapy
Contraindications
- Hypersensitivity to dactinomycin
- Active varicella or herpes zoster
- Pregnancy
Common side effects
- Myelosuppression
- Nausea
- Vomiting
- Fatigue
Counselling Points
- Monitor for signs of toxicity
- Avoid contact with skin and eyes
- Report any adverse reactions immediately
Serious warnings
- Highly toxic
- Corrosive
- Risk of severe tissue damage on extravasation
Important Disclaimer
The Cosmegen 0,5 Mg 0,5 mg POWDER FOR SOLUTION FOR INJECTION professional information leaflet below is the property of Key Oncologics and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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