Deferiprone Key 500 mg FC tablets
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of iron overload in thalassaemia major.
Dosage (summary)
25 mg/kg three times daily, max 75 mg/kg/day.
Special Populations
- Renal impairment
- Hepatic impairment
- Paediatric population
Pregnancy & Breastfeeding
Contraindicated in pregnancy and breastfeeding.
Key Drug Interactions
- Aluminium-based antacids
- Vitamin C
Contraindications
- Hypersensitivity
- Neutropenia
- Agranulocytosis
- Pregnancy
- Breastfeeding
Common side effects
- Nausea
- Vomiting
- Abdominal pain
- Chromaturia
Counselling Points
- Monitor for signs of infection
- Avoid pregnancy
- Urine may discolor
Serious warnings
- Neutropenia
- Agranulocytosis
- Carcinogenic potential
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