Aspen Epirubicin Injection
Clinical Summary
Quick overview from the medicine insert
Indication
Monotherapy for various neoplasms including breast and gastric carcinomas.
Dosage (summary)
60 to 90 mg/mu00b2 body surface area, repeated every 21 days; up to 135 mg/mu00b2 for advanced breast cancer.
Special Populations
- Elderly
- Hepatic impairment
Pregnancy & Breastfeeding
Not established; avoid pregnancy and breastfeeding.
Key Drug Interactions
- Cimetidine increases epirubicin concentration
- Avoid mixing with heparin
- Cardio-active compounds may increase cardiotoxicity
Common side effects
- Leucopenia
- Nausea
- Vomiting
- Alopecia
- Cardiotoxicity
Counselling Points
- Monitor for signs of infection
- Avoid contact sports
- Report any bleeding or bruising
Serious warnings
- Cardiac monitoring required
- Risk of myelosuppression
- Avoid immunisations without approval
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