Nexiam 5 mg, 2,5 mg Sachets

Nexiam 5 mg, 2,5 mg Sachets

S4
PDF Leaflet Revision Date: 20 May 2021


Clinical Summary

Quick overview from the medicine insert

Indication

Treatment of Gastro-Oesophageal Reflux Disease (GORD).

Dosage (summary)

2.5 mg to 10 mg once daily for infants; 20 mg to 40 mg once daily for adults.

Onset of Action / Duration

Onset: 1 hour, Duration: 13-17 hours.

Special Populations

  • Elderly
  • Renal impairment
  • Hepatic impairment

Pregnancy & Breastfeeding

Safety not established during pregnancy and lactation.

Key Drug Interactions

  • Inhibits CYP2C19
  • Increased digoxin absorption
  • Increased warfarin INR

Contraindications

  • Hypersensitivity to esomeprazole or benzimidazoles

Common side effects

  • Headache
  • Abdominal pain
  • Diarrhoea
  • Nausea/vomiting

Counselling Points

  • Take with non-carbonated water.
  • Monitor for gastrointestinal symptoms.
  • Report any allergic reactions.

Serious warnings

  • May mask gastric malignancy symptoms
  • Increased risk of gastrointestinal infections
Important Disclaimer

The Nexiam 5 mg, 2,5 mg Sachets professional information leaflet below is the property of Astrazeneca Pharmaceuticals and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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