Lucrin Depot 11,25 –Lucrin Depot Diluent 11,25 mg Lyophilised microspheres for injection, Sterile diluent for injection
Clinical Summary
Quick overview from the medicine insert
Indication
Palliative treatment of advanced prostatic cancer, endometriosis, uterine fibroids, and as adjuvant therapy in breast cancer.
Dosage (summary)
11.25 mg subcutaneous or intramuscular injection every 3 months.
Special Populations
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Not established in pregnancy; contraindicated in breastfeeding.
Contraindications
- Hypersensitivity to leuprolide acetate
- Pregnancy
- Breastfeeding
- Undiagnosed vaginal bleeding
Common side effects
- Hot flushes
- Weight gain
- Erectile dysfunction
- Fatigue
- Bone pain
Counselling Points
- Monitor for signs of worsening symptoms
- Use non-hormonal contraception if needed
- Report any severe side effects immediately
Serious warnings
- Risk of anaphylaxis
- Potential for convulsions
- Increased cardiovascular risk
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