Medrol 4 mg and 16 mg Tablets
Clinical Summary
Quick overview from the medicine insert
Indication
Corticosteroid responsive diseases and various inflammatory conditions.
Dosage (summary)
Initial dosage varies from 4 to 48 mg/day; adjust based on response.
Special Populations
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Not recommended; may cause fetal malformations and low birth weight.
Key Drug Interactions
- CYP3A4 inhibitors
- CYP3A4 inducers
- Warfarin
Contraindications
- Hypersensitivity to methylprednisolone
- Systemic fungal infections
- Traumatic brain injury
Common side effects
- Increased blood glucose
- Fluid retention
- Mood swings
Counselling Points
- Monitor for infections
- Do not stop abruptly
- Report mood changes
Serious warnings
- Increased susceptibility to infections
- Adrenal insufficiency risk
- Cushing's syndrome
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