Solu-Medrol 40 Mg, 125 Mg, 500 Mg, 1 000 Mg Injection 40 mg, 125 mg, 500 mg, 1 000 mg Powder for solution for injection
PDF Leaflet Revision Date: 27 March 2025
Clinical Summary
Quick overview from the medicine insert
Indication
Indicated for corticosteroid responsive diseases and endocrine disorders.
Dosage (summary)
IV: 30 mg/kg for life-threatening conditions; 1 g/day for 3 days for lupus or MS.
Special Populations
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Not recommended; may cause fetal malformations and low birth weight.
Key Drug Interactions
- CYP3A4 inhibitors
- CYP3A4 inducers
- Anticoagulants
Contraindications
- Hypersensitivity to methylprednisolone
- Systemic fungal infections
- Intrathecal administration
Common side effects
- Infections
- Mood swings
- Increased blood glucose
Counselling Points
- Monitor for signs of infection
- Gradual dosage reduction required
- Avoid live vaccines
Serious warnings
- Increased susceptibility to infections
- Adrenal insufficiency risk
- Potential for severe psychiatric effects
Important Disclaimer
The Solu-Medrol 40 Mg, 125 Mg, 500 Mg, 1 000 Mg Injection 40 mg, 125 mg, 500 mg, 1 000 mg Powder for solution for injection professional information leaflet below is the property of Pfizer Laboratories and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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