Bayquin Tablets 400mg FC tablets

Indication

Treatment of bacterial infections including respiratory tract infections, skin and soft tissue infections, and intra-abdominal infections.

Dosage (summary)

The usual adult dosage is 400 mg once daily, administered orally, with or without food.

Onset of Action / Duration

Onset of action typically occurs within 1 to 2 hours after administration, with peak plasma concentrations reached in approximately 1 to 2 hours.

Special Populations

• Elderly patients may require dose adjustment due to renal function.
• Patients with renal impairment should have their dosage adjusted based on creatinine clearance.
• Patients with hepatic impairment may require caution and monitoring.

Pregnancy & Breastfeeding

Moxifloxacin should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not recommended during breastfeeding.

Key Drug Interactions

• Antacids containing magnesium or aluminum may reduce the absorption of Moxifloxacin.
• Concurrent use with other QT-prolonging drugs may increase the risk of arrhythmias.
• Warfarin: Moxifloxacin may enhance the anticoagulant effect of warfarin.

Contraindications

• Hypersensitivity to Moxifloxacin or any other fluoroquinolone.
• History of tendon disorders related to fluoroquinolone use.
• Patients with a history of myasthenia gravis.

Common side effects

• Nausea
• Diarrhea
• Dizziness
• Headache
• QT interval prolongation
• Tendon rupture

Counselling Points

• Advise patients to complete the full course of therapy even if symptoms improve.
• Instruct patients to stay hydrated and report any signs of tendon pain or swelling.
• Caution patients about potential dizziness and to avoid driving or operating heavy machinery until they know how the medication affects them.