Cardioplegic Induction Solution Fresenius 3.757 g/500 m AND 1.375 g/500 ml Solutions for infusion
Clinical Summary
Quick overview from the medicine insert
Indication
For blood cardioplegic cardiac bypass procedures.
Dosage (summary)
Induction: 300 ml/min for 3 mins; Maintenance: every 20 mins during surgery.
Special Populations
- Children
- Geriatric patients
Pregnancy & Breastfeeding
Safety in pregnancy and lactation not established.
Key Drug Interactions
- Lithium
- Potassium-sparing diuretics
- NSAIDs
Contraindications
- Hypersensitivity to potassium chloride
- Hyperchloremia
- Severe renal insufficiency
- Uncompensated heart failure
- Addison's disease
Common side effects
- Hyperkalaemia
- Hyponatraemia
- Anaphylactic reaction
- Infusion site pain
Counselling Points
- Monitor serum electrolytes and ECG
- Discard unused solution
- Use aseptic technique when adding glucose
Serious warnings
- Risk of hyperkalaemia
- Risk of hyponatraemic encephalopathy
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