Angeliq 1.0 mg/2.0 mg FC tablets
Clinical Summary
Quick overview from the medicine insert
Indication
Hormone replacement therapy in postmenopausal women to relieve menopausal symptoms and to prevent osteoporosis.
Dosage (summary)
One tablet daily, taken orally at the same time each day.
Onset of Action / Duration
Symptomatic relief may be observed within a few weeks, with maximum effect typically seen after several months of therapy.
Special Populations
- Elderly patients
- Patients with liver impairment
- Patients with a history of thromboembolic disorders
Pregnancy & Breastfeeding
Not recommended during pregnancy. Use with caution during lactation as it may affect milk production.
Key Drug Interactions
- Anticonvulsants may reduce the effectiveness of progesterones.
- Certain antibiotics (e.g., rifampicin) may decrease the effectiveness of hormonal contraceptives.
- St. John's Wort may reduce plasma concentrations of progesterones.
Contraindications
- Known or suspected pregnancy
- Active or history of thromboembolic disorders
- Severe liver disease
- Hormone-sensitive cancers
Common side effects
- Nausea
- Headache
- Breast tenderness
- Mood changes
- Weight gain
Counselling Points
- Advise patients to take the medication at the same time each day.
- Inform patients about potential side effects and when to seek medical advice.
- Discuss the importance of regular follow-up appointments to monitor therapy.
Serious warnings
- Monitor for signs of thromboembolic events.
- Use with caution in patients with a history of depression.
- Discontinue use if unexplained vaginal bleeding occurs.
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