Mestinon 10 mg or 60 mg Tablets
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of myasthenia gravis.
Dosage (summary)
Adults: 1-3 tablets (60 mg) 2-4 times daily; Children: 7 mg/kg daily.
Special Populations
- Renal impairment
- Elderly patients
- Obstructive respiratory diseases
Pregnancy & Breastfeeding
Safety during pregnancy and breastfeeding not established.
Key Drug Interactions
- Corticosteroids may decrease MESTINON requirement
- Antimuscarinics antagonize muscarinic effects
- Aminoglycoside antibiotics may interact
Contraindications
- Hypersensitivity to pyridostigmine or bromides
- Mechanical intestinal or urinary obstruction
Common side effects
- Muscle cramps
- Fasciculation
- Nausea
- Diarrhoea
- Bradycardia
Counselling Points
- Monitor for signs of overdose
- Report any severe side effects
- Take with caution if pregnant or breastfeeding
Serious warnings
- Risk of cholinergic crisis
- Caution in patients with arrhythmias
- Care in renal impairment
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