Seroquel XR 50mg. 150mg. 200mg. 300mg. 400mg Tablet

Seroquel XR 50mg. 150mg. 200mg. 300mg. 400mg Tablet

S5
PDF Leaflet Revision Date: 12 May 2023


Clinical Summary

Quick overview from the medicine insert

Indication

Treatment of schizophrenia and bipolar disorder.

Dosage (summary)

Adults: Start at 300 mg, increase to 800 mg as needed. Elderly: Start at 50 mg, adjust as tolerated.

Onset of Action / Duration

Onset: 1-2 weeks, Duration: 24 hours

Special Populations

  • Elderly
  • Hepatic impairment

Pregnancy & Breastfeeding

Contraindicated during pregnancy and lactation.

Key Drug Interactions

  • CYP3A4 inhibitors
  • Hepatic enzyme inducers

Contraindications

  • Hypersensitivity to quetiapine

Common side effects

  • Somnolence
  • Dizziness
  • Dry mouth
  • Constipation
  • Tachycardia

Counselling Points

  • Monitor for signs of hyperglycaemia
  • Avoid alcohol
  • Gradual withdrawal recommended

Serious warnings

  • Risk of hyperglycaemia
  • Neuroleptic malignant syndrome
  • QT prolongation
Important Disclaimer

The Seroquel XR 50mg. 150mg. 200mg. 300mg. 400mg Tablet professional information leaflet below is the property of Astrazeneca and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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