Seroquel 25 mg, 100 mg, 200 mg, 300 mg, Tablet
PDF Leaflet Revision Date: 08 January 2024
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of schizophrenia and manic episodes associated with bipolar disorder.
Dosage (summary)
Adults: Start with 50 mg on Day 1, titrate to 300-450 mg/day for schizophrenia; 100 mg on Day 1, titrate to 400-800 mg/day for bipolar disorder.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and lactation; safety not demonstrated.
Key Drug Interactions
- CNS depressants
- QT interval prolonging drugs
- Anticholinergic medications
Contraindications
- Hypersensitivity to components
- Severe liver and renal impairment
- Children and adolescents
Common side effects
- Somnolence
- Dizziness
- Dry mouth
- Weight gain
- Extrapyramidal symptoms
Counselling Points
- Monitor for signs of suicidal thoughts
- Caution with alcohol and CNS depressants
- Gradual withdrawal recommended
- Report any severe skin reactions
Serious warnings
- Risk of suicide
- Neutropenia and agranulocytosis
- Hyperglycaemia and diabetes
- QT prolongation
Important Disclaimer
The Seroquel 25 mg, 100 mg, 200 mg, 300 mg, Tablet professional information leaflet below is the property of Astrazeneca Pharmaceuticals and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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