Risperdal 1mg / 1ml Oral Solution
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of schizophrenia, mania in bipolar disorder, and disruptive behavior disorders in children.
Dosage (summary)
Adults: Start at 2 mg/day, increase to 4 mg/day on day 2; maintenance 4-8 mg/day. Elderly/renal impairment: Start at 0.5 mg twice daily.
Onset of Action / Duration
Onset: 1-2 hours, Duration: 24 hours for active metabolite.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Use only if benefits outweigh risks; contraindicated in breastfeeding.
Key Drug Interactions
- Caution with alcohol and CNS depressants
- Antagonizes levodopa
- Increased mortality with furosemide
Contraindications
- Known sensitivity to components
- Children under 5 years
- Parkinsonu2019s disease
- Lewy Body Dementia
Common side effects
- Increased weight
- Tachycardia
- Parkinsonism
- Dizziness
- Somnolence
Counselling Points
- Monitor for weight gain
- Avoid dehydration
- Caution with driving or machinery
- Report signs of hyperglycemia
Serious warnings
- Increased mortality in elderly with dementia
- Cerebrovascular adverse events
- Neuroleptic Malignant Syndrome
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