Rutra Solution 1 Mg/Ml 1 mg/ml Solution
PDF Leaflet Revision Date: 29/01/2021
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of acute and chronic schizophrenia, behavioral disturbances in dementia, and disruptive behavior disorders in children.
Dosage (summary)
Adults: Start at 2 mg/day, increase to 4 mg/day on day 2, maintain 4-8 mg/day. Elderly: Start at 0.5 mg twice daily.
Onset of Action / Duration
Onset: 1-2 hours, Duration: 24 hours for active fraction.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Safety in pregnancy not established; excreted in breast milk, avoid breastfeeding.
Key Drug Interactions
- Carbamazepine decreases plasma levels
- Fluoxetine increases plasma concentration
Contraindications
- Known sensitivity to components
- Children under 5 years
- Lewy body dementia
Common side effects
- Weight gain
- Headache
- Fatigue
- Extrapyramidal symptoms
- Insomnia
Counselling Points
- Monitor for hyperglycemia
- Avoid driving until effects are known
- Weight gain possible
Serious warnings
- Tardive dyskinesia
- Neuroleptic Malignant Syndrome
- Higher mortality in elderly with furosemide
Important Disclaimer
The Rutra Solution 1 Mg/Ml 1 mg/ml Solution professional information leaflet below is the property of Aurogen South Africa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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