Sitagliptin 25/50/ 100 Adco 25 mg, 50 mg and 100 mg FC Tablets
PDF Leaflet Revision Date: 29 July 2025
Clinical Summary
Quick overview from the medicine insert
Indication
Adjunct to diet and exercise for type 2 diabetes mellitus.
Dosage (summary)
100 mg once daily; 50 mg for moderate renal impairment; 25 mg for severe renal impairment.
Special Populations
- Renal impairment
- Hepatic impairment
- Elderly
Pregnancy & Breastfeeding
Not recommended during pregnancy or breastfeeding.
Key Drug Interactions
- CYP3A4 inhibitors
- Metformin
- Digoxin
Contraindications
- Hypersensitivity to sitagliptin
- Severe hepatic insufficiency
Common side effects
- Hypoglycaemia
- Headache
- Dizziness
- Nausea
Counselling Points
- Take with or without food
- Monitor for signs of pancreatitis
- Risk of hypoglycaemia with insulin or sulphonylureas
Serious warnings
- Risk of acute pancreatitis
- Serious hypersensitivity reactions
Important Disclaimer
The Sitagliptin 25/50/ 100 Adco 25 mg, 50 mg and 100 mg FC Tablets professional information leaflet below is the property of Adcock Ingram and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
Healthcare Professionals Only
This content is for registered healthcare professionals
Sign in or create a free account to read the full package insert.
Free for HPCSA-registered professionals. Powered by Medinsert.
