Aubamide 14mg Tablet

Indication

Treatment of relapsing forms of multiple sclerosis (MS) in adults.

Dosage (summary)

The recommended dose is 14 mg once daily, taken orally, with or without food.

Onset of Action / Duration

The onset of action may take several weeks, with clinical effects observed after 2 to 3 months of treatment.

Special Populations

• Renal impairment
• Hepatic impairment
• Elderly patients

Pregnancy & Breastfeeding

Teriflunomide is contraindicated in pregnancy. Women of childbearing potential should use effective contraception during treatment and for at least 2 years after discontinuation. It is not known if teriflunomide is excreted in human breast milk; caution is advised.

Key Drug Interactions

• Other immunosuppressants may increase the risk of infections.
• Cholestyramine or activated charcoal can accelerate the elimination of teriflunomide.
• Caution with drugs that affect liver function.

Contraindications

• Pregnancy
• Severe hepatic impairment
• Hypersensitivity to teriflunomide or any component of the formulation

Common side effects

• Diarrhea
• Nausea
• Hair loss
• Elevated liver enzymes
• Infections

Counselling Points

• Advise patients to report any signs of liver dysfunction, such as jaundice or dark urine.
• Inform patients about the risk of infections and advise them to seek medical attention if they develop symptoms.
• Discuss the importance of adherence to the prescribed dosage regimen.