Tigecycline 50 Mg Pfizer 50 mg Sterile Powder for Intravenous Infusion
Clinical Summary
Quick overview from the medicine insert
Indication
Severe life-threatening infections in adults.
Dosage (summary)
Initial 100 mg IV, then 50 mg every 12 hours.
Onset of Action / Duration
Onset: Not specified, Duration: 5-14 days.
Special Populations
- Renal impairment
- Hepatic impairment
- Elderly
Pregnancy & Breastfeeding
Contraindicated in pregnancy and breastfeeding.
Key Drug Interactions
- Warfarin
- Digoxin
- Calcineurin inhibitors
Contraindications
- Hypersensitivity to tigecycline or excipients
- Pregnancy
- Lactation
Common side effects
- Nausea
- Vomiting
- Diarrhoea
- Dizziness
- Rash
Counselling Points
- Monitor for allergic reactions
- Avoid in pregnancy
- Report severe gastrointestinal symptoms
Serious warnings
- Increased all-cause mortality
- Not for HAP or VAP
- Risk of pancreatitis
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